73 -

סרטן

Non-Hodgkin `.
` - . non-Hodgkin , . non-Hodgkin , -50 - . - ( indolent), (aggressive). non-Hodgkin 13,000 ...
  Non-Hodgkin  `.
- 2018, `
: `-
- 2018, `
 -        2018,  `
- 2018, `
: `-
- 2018, `
 -        2018,  `
-
-
 -
: 8 ! `.
` - . -3 "" DNA . DNA ctDNA circulating tumor DNA, . DNA Soluble biopsies. , Science -18 , Joshua Cohen Kimmel Johns Hopkins, 40 ", ...
   :      8   !  `.
: 8 ! `.
` - . -3 "" DNA . DNA ctDNA circulating tumor DNA, . DNA Soluble biopsies. , Science -18 , Joshua Cohen Kimmel Johns Hopkins, 40 ", ...
   :      8   !  `.
: , `.
` - . - , -, , -, . , 23,380 " 2014, -14,320 : , 1.4% " -2.4% . 6.4 100,000 ", 5 33.4%...
   :  ,  `.
: , `.
` - . - , -, , -, . , 23,380 " 2014, -14,320 : , 1.4% " -2.4% . 6.4 100,000 ", 5 33.4%...
   :  ,  `.
- ? `.
` - . Allison -30 , , . 1983 Allison -Cell , T . 1992 -Nature - Allison T -CD28 (signal) , "" (anergy) . 4 Allison -Science 1994, CTLA-4 T ...
 -          ?  `.
Non-Hodgkin Lymphoma " ` `
: `-
Non-Hodgkin Lymphoma " ` `
       Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma " ` `
: `-
Non-Hodgkin Lymphoma " ` `
       Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma " `, `
: `-
Non-Hodgkin Lymphoma " ` `
       Non-Hodgkin Lymphoma
: type 2
: ` -
: type 2
    :  type 2
CD73:
: `-
CD73:
   CD73:
MGUS:
: `-
MGUS:
     MGUS:
? `.
` - . , . , . - , Herceptin -Gleevec, -5 -50% -66%. ...
              ?  `.
- ,
 - ,
Ofatumumab - FDA , `
: `-
Ofatumumab - FDA , `
Ofatumumab    - FDA    ,  `
30 : , `.
` - . , -4 " . 2009 -1,479,350 ", 562,340 . , . ...
       30  :       ,  `.
Iressa:
: `-
Iressa:
Iressa:
-4
, : , , .
 -4
- . `.
` - . 2007 obesity . , " ...
    - .  `.
- . `.
` - . 2007 obesity . , " ...
    - .  `.
`
` () . Ginsenoside Rg1 ...
`
? `.
` - . 389,000 , 3.6% . , , ...
    ?   `.
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